Platelet activation following application of an esmarch bandage and tourniquet in rabbits

The present study evaluates platelet activation following application of an Esmarch bandage and a tourniquet, procedures commonly employed to provide a bloodless operative field during limb surgery. Platelet aggregation was increased in blood samples taken from rabbits 60 min after an Esmarch bandage was applied to one thigh and immediately released. When this treatment was combined with the application of a tourniquet for 60 min, a procedure which alone did not affect platelet aggregation, results were similar to those obtained following the Esmarch bandage alone. These data suggest that tissue compression produced by application of an Esmarch bandage, but not the ischemia derived from the tourniquet, produced platelet aggregation

Comparative study of the action of topical heparinoids on the evolution of experimental thrombophlebitis

The action of threem different topical heparinoids on the evolution of experimental thrombophlebitis was studies. Thrombophlebitis was induced in the marginal vein of the ear of rabbits by stasis and inection of hypertonic glucose solution. Forty-eight hours later animals were allocated to three treatment groups and a control group. The substances were applied over the affected vein three times a day for 6 days and the ears inspected daily by transillumination. After 7 days, the animals were killed and anatomopathological studies performed. No difference in thrombus frequency or inflamatory reaction was observed between the animals treated with heparinoids and the control group, or among the treated groups

Tratamento de trombose venosa profunda com doses fixas de heparina subcutanea. / Treatment of deep venous thrombosis with fixed doses of subcutaneous heparin

Com base na observacao de bons resultados em alguns casos de TVP excepcionalmente tratados com heparina subcutanea e em dados de literatura, os autores compararam prospectivamente um grupo de 19 pacientes portadores de trombose venosa profunda dos membros, tratados com heparina subcutanea em doses fixas de 30.000U/dia durante 10 dias, com um grupo de 17 pacientes tratados com heparina intravenosa em administracao continua, controlada pelo tempo de tromboplastina parcial ativada. Os pacientes foram controlados clinicamente e por flebografias realizadas antes e apos o tratamento. Nao se verificou diferenca na evolucao clinica ou flebografica entre os pacientes tratados com um outro regime.Nenhum doente apresentou quadro clinico sugestivo de embolia pulmonar ou complicacao hemorragica. Os resultados obtidos ate o presente sugerem que o tratamento da TVB distal dos membros com doses fixas de heparina por via subcutanea podera vir a ser um tratamento alternativo, justificando a continuacao de pesquisas nesse sentido

Cisto de adventicia em arteria poplitea. Relato de dois casos. / Adventitial cyst in popliteal artery. Report of 2 cases

Por ser uma afeccao de diagnostico raro no Brasil, os autores apresentam dois casos de cisto de adventicia em arteria poplitea em pacientes masculinos, tratados no Hospital das Clinicas da Faculdade de Medicina de Botucatu. Os achados clinicos, radiologicos, histopatologicos e o tratamento sao descritos e comparados com os da literatura